Oncology trials, reimagined
Curing cancer starts with better trials.
AI-powered digital twins for oncology trials.
Twintafo helps trial teams simulate outcomes, stress-test design decisions, and evaluate external controls before investing millions in real-world studies.
Built for biotech, pharma, CROs, and biostatistics teams.
Why oncology trials stall
Traditional trials carry high uncertainty, slow recruitment,\nand hard-to-control variability.
Oncology trial planning has a narrow margin for error. One slow cohort or misaligned endpoint can add quarters to a program and compound risk across the pipeline.
Twintafo surfaces these pressure points early, before teams commit real patients and real budgets.
Recruitment takes too long
Enrollment bottlenecks delay timelines and inflate trial costs year over year.
Control arms are difficult to enroll
Patients often avoid or drop from control cohorts, undermining power and balance.
Populations differ across sites
Heterogeneous cohorts create unpredictable variability and complicate analysis.
Small design choices create major bias
Minor protocol tweaks can shift outcomes and derail interpretation.
Simulate before you commit.
Twintafo creates realistic synthetic patient journeys to test trial assumptions, compare strategies, and quantify risk before real patients are enrolled.
01
Simulate
Model realistic trial outcomes before the first patient visits.
02
Compare
Stress-test arms, endpoints, and assumptions side-by-side.
03
Decide
Quantify tradeoffs and choose a design with conviction.
A focused three-step loop
A structured flow from assumptions to digital twins to actionable diagnostics.
Define simulations
Align on design, endpoints, and population profiles.
Generate digital twins
Create synthetic longitudinal patient cohorts.
Stress-test outcomes
Evaluate power, bias, timelines, and robustness.
Built for trial decision-makers
Designed for teams driving oncology programs with high stakes and tight timelines.
Audience
Biotech & Pharma
De-risk oncology programs before pivotal investment.
Focused on faster evidence without sacrificing scientific rigor.
Audience
CROs
Strengthen proposals with simulation-backed evidence.
Focused on faster evidence without sacrificing scientific rigor.
Audience
Biostatistics teams
Pressure-test design decisions with transparent assumptions.
Focused on faster evidence without sacrificing scientific rigor.
Built with early collaborators.
We’re currently working with early design partners to shape the Twintafo platform.
Deliverables may include
- Trial simulation plans
- Synthetic longitudinal datasets
- Sensitivity analyses
- Structured decision summaries
Every collaboration is tailored, with artifacts sized to your decision timeline and evidence needs.
Engagement arc
01 — Scope the trial
Define endpoints, cohorts, and decision criteria.
02 — Run simulations
Generate digital twins and stress-test scenarios.
03 — Decide with evidence
Translate diagnostics into a confident next step.
Built for rigor.
A platform designed to deliver insight without compromising privacy or reproducibility.
Questions teams ask early
Concise answers to common questions from oncology trial teams.
No. Twintafo provides synthetic counterparts to help trial teams explore design decisions before enrollment.
Build the trial before you run it.
Collaborate with Twintafo to pressure-test your next oncology trial before it starts.
Start the conversation.
Tell us about your trial goals, and we’ll outline a tailored simulation plan.
What happens next
We align on your trial questions, constraints, and success criteria, then outline a focused simulation plan.